Cite GPCRchimeraDB

Reference for GPCRchimeraDB

If you use GPCRchimeraDB, please cite:

Crauwels, C., Díaz, A., & Vranken, W. F. (2024). GPCRchimeraDB: A database of chimeric G protein-coupled receptors (GPCRs) to assist their design. Journal of Molecular Biology. https://doi.org/10.1016/j.jmb.2025.169164

Authors and Affiliations

The authors of GPCRchimeraDB are Charlotte Crauwels (PhD student) and Adrián Díaz (software engineer), under the supervision of Prof. Wim Vranken. We are part of the Bio2Byte research group led by Prof. Wim Vranken, the Interuniversity Institute of Bioinformatics in Brussels (IB2), Structural Biology Brussels (SBB) and the AI lab of the Vrije Universiteit Brussel (VUB).

More information about our current and previous work at Bio2Byte here.

Acknowledgements

We thank the Bio2Byte research group for their testing and feedback to help us improve GPCRchimeraDB. We also highly appreciated the feedback provided by Prof. Julien Hanson and his group, as well as by Dr. Sarah Triest. Finally, we would like to express our gratitude to Dr. Zara Sands for her ideas, feedback, and enthusiasm during the early stages of development of this database.

Funding

This work was supported by the Research Foundation Flanders (FWO) SB PhD fellowship [1SE5925N to C.C.]; and the FWO International Research Infrastructure [I000323N to W.V. and G032816N to A.D.]. The resources used in this work were provided in part by the VSC (Flemish Supercomputer Center), funded by the FWO and the Flemish Government.